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  • PYGM gene: MedlinePlus Genetics
    The PYGM gene provides instructions for making an enzyme called myophosphorylase Learn about this gene and related health conditions
  • Myophosphorylase - Wikipedia
    Myophosphorylase or glycogen phosphorylase, muscle associated (PYGM) is the muscle isoform of the enzyme glycogen phosphorylase and is encoded by the PYGM gene
  • PYGM Gene - GeneCards
    PYGM (Glycogen Phosphorylase, Muscle Associated) is a Protein Coding gene Diseases associated with PYGM include Glycogen Storage Disease V and Glycogen Storage Disease Among its related pathways are glycogen degradation II and glycogenolysis An important paralog of this gene is PYGB
  • Entry - *608455 - GLYCOGEN PHOSPHORYLASE, MUSCLE; PYGM - OMIM
    The PYGM gene encodes the muscle isoform of glycogen phosphorylase (EC 2 4 1 1), which catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate during glycogenolysis
  • PYGM - Glycogen phosphorylase, muscle form - Oryctolagus cuniculus . . .
    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis This reaction proceeds in the forward direction
  • PYGM Protects Against Myocardial Infarction by Enhancing Glycogenolysis . . .
    PYGM (muscle glycogen phosphorylase), the rate-limiting enzyme in glycogenolysis, plays an indispensable role in maintaining cardiac energy metabolism However, the role of PYGM in the pathogenesis of myocardial infarction (MI) remains unclear
  • Test Catalog - Baylor Genetics
    The PYGM Sequencing Analysis is performed to identify pathogenic variants associated with glycogen storage disease type V Glycogen storage disease type V (GSDV), also known as McArdle Disease, is a metabolic disorder that affects the muscles and is characterized by exercise intolerance, rapid fatigue, myalgia, rhabdomyolysis, and cramping
  • PYGM Gene Analysis in Glycogen Storage Disease type V (GSD V)
    GSD V is caused by pathogenic variants in the PYGM gene that encodes the skeletal muscle isoform of glycogen phosphorylase known as myophosphorylase Myophosphorylase deficiency leads to the inability to use muscle glycogen
  • PYGM protein expression summary - The Human Protein Atlas
    Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines





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